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Escin Iib
CAS No. 158800-83-0
Escin Iib ( —— )
产品货号. M21791 CAS No. 158800-83-0
Escin IIb 是从七叶树（七叶树的种子）中分离出来的，对动物的急性炎症具有积极作用。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 10MG | ￥2349 | 有现货 |
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| 100MG | 获取报价 | 有现货 |
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| 200MG | 获取报价 | 有现货 |
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| 500MG | 获取报价 | 有现货 |
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| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Escin Iib
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Escin IIb 是从七叶树（七叶树的种子）中分离出来的，对动物的急性炎症具有积极作用。
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产品描述Escin IIb, isolated from horse chestnut, the seeds of Aesculus hippocastanum L., has positive effects on acute inflammation in animals. Escin IIb showed potent protective effects against ethanol-induced gastric mucosal lesions.
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体外实验——
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体内实验Escins Ia, Ib, IIa, and IIb (50-200 mg/kg) inhibit the increase of vascular permeability induced by both acetic acid in mice and histamine in rats. Escins Ib, IIa, and IIb (50-200 mg/kg) also inhibit that induced by serotonin in rats, but escin Ia didn't. Escins Ia, Ib, IIa, and IIb (200 mg/kg) inhibit the hind paw edema induced by carrageenin at the first phase in rats. Escin Ia (200 mg/kg) and escins Ib, IIa, and IIb (50-200 mg/kg) inhibit the scratching behavior induced by compound 48/80 in mice, but escin Ia was weakest.Escin IIb (10-50 mg/kg; p.o.) potently inhibits ethanol-induced gastric mucosal lesions. Animal Model:Male Sprague–Dawley rats (Ethanol-induced gastric mucosal lesions in rats)Dosage:P.o.Administration:10-50 mg/kg Result:Showed a potent protective effect against ethanol-induced gastric lesions in rats.
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同义词——
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通路Others
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靶点Other Targets
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受体——
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研究领域——
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适应症——
化学信息
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CAS Number158800-83-0
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分子量1101.23
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分子式C??H??O??
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纯度>98% (HPLC)
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溶解度——
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SMILESOC[C@]12[C@](CC(C)(C)[C@@H](OC(/C(C)=C\C)=O)[C@@H]2OC(C)=O)([H])C3=CC[C@@]([C@@]4([C@@]([C@@](CO)([C@@H](O[C@H]5[C@H](O[C@H]6[C@H](O)[C@@H](O)[C@H](O)CO6)[C@@H](O)[C@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)[C@@H](C(O)=O)O5)CC4)C)([H])CC8)C)([H])[C@]8(C)[C@]3(C)C[C@H]1O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Matsuda H, et al. Effects of escins Ia, Ib, IIa, and IIb from horse chestnut, the seeds of Aesculus hippocastanum L., on acute inflammation in animals. Biol Pharm Bull. 1997;20(10):1092-1095.
2. Matsuda H, et al. Gastroprotections of escins Ia, Ib, IIa, and IIb on ethanol-induced gastric mucosal lesions in rats. Eur J Pharmacol. 1999;373(1):63-70.
